Found 10 matching trials
Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB) PHASE3 This is a phase 3, multicenter, randomized, open-label, parallel-group, con...
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UCLA Health - Ronald Reagan Medical Center
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Patient Blood Management for Massive Obstetric Hemorrhage NA Obstetric Hemorrhage continues to be the first cause of maternal morbidity ...
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Hospital de Especialidades Del Niño Y La Mujer
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Study of Octaplex, a Four-factor Prothrombin Complex Concentrate (4F-PCC) and Beriplex® P/N (Kcentra) for the Reversal of Vitamin K Antagonist (VKA) Induced Anticoagulation in Patients Needing Urgent Surgery With Significant Bleeding Risk. PHASE3 To demonstrate that the efficacy of OCTAPLEX as a reversal agent in patient...
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Octapharma Research Site
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Active-control Randomized Trial Comparing 4-factor Prothrombin Complex Concentrate With Frozen Plasma in Cardiac Surgery PHASE3 This is a multicenter, active-control randomized, prospective, Phase 3 stud...
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Duke University Health System
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Factor In the Initial Resuscitation of Severe Trauma 2 Patients PHASE4 Injury is the leading cause of death for people between the ages of 1-44. T...
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Vancouver General Hospital
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Efficacy and Safety of Early Use PCC in Severe Trauma NA Uncontrolled hemorrhage within 24 hours after severe trauma is the main cau...
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A Study to Assess the Effects of 2 Prothrombin Complex Concentrates on the Pharmacodynamics of Apixaban in Healthy Adult Subjects PHASE1 The purpose of this study is to assess the effect of two 4-Factor PCC formu...
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Multiple Locations
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A Study to Assess the Effects of 2 Different Prothrombin Complex Concentrates on the Pharmacodynamics of Rivaroxaban in Healthy Adult Volunteers PHASE1 The purpose of this study is to assess the use of 2 different Prothrombin C...
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Multiple Locations
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Study of OCTAPLEX in Patients With Acute Major Bleeding on DOAC Therapy With Factor Xa Inhibitor PHASE3 This is a multicentre, prospective, randomised, double-blinded, group-seque...
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Harbor-UCLA Medical Center
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IMMUNINE Pre-Treatment Study PHASE4 The primary objective of this study is to prospectively document the exposu...
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Hospital JR Vidal (Servicio de Hemotologie - Area de Investiagacion
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